二相药物代谢酶的转录调控
丁月妮;柯尊平;高爱梅;
摘要：
<正>药物、毒物、致癌物等外来物质在体内一般经历两相代谢过程。一相代谢过程主要是在P450酶系的参与下,对外来物质进行氧化、还原、羟化、水解,使其大部分失活。二相代谢过程主要是在有关酶的催化下,将内源性极性小分子物质,经共价键结合到外来物质或一相代谢活化物的分
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