葛庆峰,王志军,周建芝

• 1:华北煤炭医学院附属医院,华北煤炭医学院附属医院,华北煤炭医学院校医院 (063000) ,(063000)

摘要：

目的了解高血压患者的心脏舒张期顺应性改变与各研究因素之间的关系,从而筛选出可能影响心脏舒张功能相关因素。方法应用回顾性研究的方法调查274例高血压患者,获得一般情况、血压水平、遗传史、用药史、血生化指标、心脏结构功能等指标。应用Epidate软件建立数据库,SPSS11.5软件进行数据分析。结果在超声心动图检查EF≥45%的274例患者中,伴E/A值异常的184例(67.2%)。分析结果:年龄、高血压病史年数、合并心脏扩大、冠心病、心肌梗死、脑卒中等临床情况、糖尿病、血脂异常、动脉硬化等指标在E/A值正常组和异常组之间差异有统计学意义。结论高龄、多年高血压病史、合并临床情况、糖尿病、血脂异常、合并周围血管动脉硬化等是高血压患者舒张期顺应性下降的危险因素、从而反映心脏舒张功能异常的可能危险因素。

关键词： 高血压;危险因素;舒张期顺应性下降

Abstract: Objective Understanding the changes of cardiac diastolic compliance of hypertensives and their relations with various factors so as to screen some correlation factors able to influence the cardiac diastolic function.Methods A retrospective analysis was used to survey 274 hypertensives to obtain data about their health condition,blood pressure,inherited disease,medication history,blood biochemical indices,as well as cardiac structure and function;using Epidate software to set up a data bank;processing the data with SPSS 11.5 software.Results Ultrasonic cardiographic exam showed of the 274 cases with EF≥45%,184 had abnormal value of E/A (67.2%).Analysis showed there existed significant difference between E/A normal group and E/A abnormal group in respect of the following items or indices:age,length of hypertension history,concurrent cardiomegaly,coronary heart disease,myocardial infarction,cerebral apoplexy,diabetes,abnormal blood fat,and arteriosclerosis.Conclusion Advanced age,longer hypertension history,some combined clinical symptoms,diabetes,abnormal blood fat,and concurrent peripheral arteriosclerosis are the possible risk factors for the hypertensives who have a decreased diastolic compliance following an abnormal diastolic function.

Keywords: Hypertension; Risk factor; Diastolic compliance,decreased

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